Representative publications by DHPSP members


Bulten W, Kartasalo K, Chen PC, Ström P, Pinckaers H, Nagpal K, Cai Y, Steiner DF, van Boven H, Vink R, Hulsbergen-van de Kaa C, van der Laak J, Amin MB, Evans AJ, van der Kwast T, Allan R, Humphrey PA, Grönberg H, et al. Artificial intelligence for diagnosis and Gleason grading of prostate cancer: the PANDA challenge. Nat Med. 2022 Jan;28(1):154-163. doi: 10.1038/s41591-021-01620-2.

Ehteshami Bejnordi B, Veta M, Johannes van Diest P, van Ginneken B, Karssemeijer N, Litjens G, van der Laak JAWM; et al. Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer. JAMA. 2017 Dec 12;318(22):2199-2210. doi: 10.1001/jama.2017.14585.

Lordan R, FitzGerald GA, Grosser T. Reopening schools during COVID-19. Science. 2020 Sep 4;369(6508):1146. doi: 10.1126/science.abe5765

Yastrebov K, Aneman A, Schulz L, Hamp T, McCanny P, Parkin G, Myburgh J. Comparison of echocardiographic and invasive measures of volaemia and cardiac performance in critically ill patients. Sci Rep. 2020 Mar 17;10(1):4863. doi: 10.1038/s41598-020-61761-1

Komorowski M, Celi LA, Badawi O, Gordon AC, Faisal AA. The Artificial Intelligence Clinician learns optimal treatment strategies for sepsis in intensive care. Nat Med. 2018 Nov;24(11):1716-1720. doi: 10.1038/s41591-018-0213-5

Wang D, Day EA, Townsend LK, Djordjevic D, Jørgensen SB, Steinberg GR. GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease. Nat Rev Endocrinol. 2021 Oct;17(10):592-607. doi: 10.1038/s41574-021-00529-7

Yeung AWK, Wochele-Thoma T, Eibensteiner F, Klager E, Hribersek M, Parvanov ED, Hrg D, Völkl-Kernstock S, Kletecka-Pulker M, Schaden E, Willschke H, Atanasov AG. Official Websites Providing Information on COVID-19 Vaccination: Readability and Content Analysis. JMIR Public Health Surveill. 2022 Mar 15;8(3):e34003. doi: 10.2196/34003

van der Laak J, Ciompi F, Litjens G. No pixel-level annotations needed. Nat Biomed Eng. 2019 Nov;3(11):855-856. doi: 10.1038/s41551-019-0472-6.

Yeung AWK, Atanasov AG, Sheridan H, Klager E, Eibensteiner F, Völkl-Kernsock S, Kletecka-Pulker M, Willschke H and Schaden E (2021) Open Innovation in Medical and Pharmaceutical Research: A Literature Landscape Analysis. Front. Pharmacol. 11:587526. doi: 10.3389/fphar.2020.587526

Britton OJ, Bueno-Orovio A, Van Ammel K, Lu HR, Towart R, Gallacher DJ, Rodriguez B. Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):E2098-105. doi: 10.1073/pnas.1304382110.

Genschow O, Klomfar S, d’Haene I, Brass M. Mimicking and anticipating others’ actions is linked to Social Information Processing. PLoS One. 2018 Mar 28;13(3):e0193743. doi: 10.1371/journal.pone.0193743.

Peng H, Ruan Z, Long F, Simpson JH, Myers EW. V3D enables real-time 3D visualization and quantitative analysis of large-scale biological image data sets. Nat Biotechnol. 2010 Apr;28(4):348-53. doi: 10.1038/nbt.1612

Lawson BAJ, Drovandi CC, Cusimano N, Burrage P, Rodriguez B, Burrage K. Unlocking data sets by calibrating populations of models to data density: A study in atrial electrophysiology. Sci Adv. 2018 Jan 10;4(1):e1701676. doi: 10.1126/sciadv.1701676.

Eliceiri KW, Berthold MR, Goldberg IG, Ibáñez L, Manjunath BS, Martone ME, Murphy RF, Peng H, Plant AL, Roysam B, Stuurman N, Swedlow JR, Tomancak P, Carpenter AE. Biological imaging software tools. Nat Methods. 2012 Jun 28;9(7):697-710. doi: 10.1038/nmeth.2084

Atanasov AG, Yeung AWK, Klager E, Eibensteiner F, Schaden E, Kletecka-Pulker M and Willschke H (2020) First, Do No Harm (Gone Wrong): Total-Scale Analysis of Medical Errors Scientific Literature. Front. Public Health 8:558913. doi: 10.3389/fpubh.2020.558913

Meijering E, Carpenter AE, Peng H, Hamprecht FA, Olivo-Marin JC. Imagining the future of bioimage analysis. Nat Biotechnol. 2016 Dec 7;34(12):1250-1255. doi: 10.1038/nbt.3722

Singh BN, Prateeksha, Gupta VK, Chen J, Atanasov AG. Organic Nanoparticle-Based Combinatory Approaches for Gene Therapy. Trends Biotechnol. 2017 Dec;35(12):1121-1124. doi: 10.1016/j.tibtech.2017.07.010

Ting DSW, Cheung CY, Lim G, Tan GSW, Quang ND, Gan A, Hamzah H, Garcia-Franco R, San Yeo IY, Lee SY, Wong EYM, Sabanayagam C, Baskaran M, Ibrahim F, Tan NC, Finkelstein EA, Lamoureux EL, Wong IY, Bressler NM, Sivaprasad S, Varma R, Jonas JB, He MG, Cheng CY, Cheung GCM, Aung T, Hsu W, Lee ML, Wong TY. Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes. JAMA. 2017 Dec 12;318(22):2211-2223. doi: 10.1001/jama.2017.18152

Yeung AWK, Tosevska A, Klager E, Eibensteiner F, Laxar D, Stoyanov J, Glisic M, Zeiner S, Kulnik ST, Crutzen R, Kimberger O, Kletecka-Pulker M, Atanasov AG, Willschke H. Virtual and Augmented Reality Applications in Medicine: Analysis of the Scientific Literature. J Med Internet Res. 2021 Feb 10;23(2):e25499. doi: 10.2196/25499

Ting DSW, Carin L, Dzau V, Wong TY. Digital technology and COVID-19. Nat Med. 2020 Apr;26(4):459-461. doi: 10.1038/s41591-020-0824-5

Keshavarzi Arshadi A, Webb J, Salem M, Cruz E, Calad-Thomson S, Ghadirian N, Collins J, Diez-Cecilia E, Kelly B, Goodarzi H and Yuan JS (2020) Artificial Intelligence for COVID-19 Drug Discovery and Vaccine Development. Front. Artif. Intell. 3:65. doi: 10.3389/frai.2020.00065

Cheung CY, Xu D, Cheng CY, Sabanayagam C, Tham YC, Yu M, Rim TH, Chai CY, Gopinath B, Mitchell P, Poulton R, Moffitt TE, Caspi A, Yam JC, Tham CC, Jonas JB, Wang YX, Song SJ, Burrell LM, Farouque O, Li LJ, Tan G, Ting DSW, Hsu W, Lee ML, Wong TY. A deep-learning system for the assessment of cardiovascular disease risk via the measurement of retinal-vessel calibre. Nat Biomed Eng. 2021 Jun;5(6):498-508. doi: 10.1038/s41551-020-00626-4

Yeung AWK, Tanaka R, Ho JKC, Li JQ, Jacobs R, Bornstein MM. Patient-,
software-, and observer-related factors associated with the time required for
semi-automated measurements of the maxillary sinus volume using cone beam
computed tomography (CBCT)
. Swiss Dent J. 2019 Jul 22;129(7-8):562-570.

Eibensteiner, F., Ritschl, V., Ariceta, G. et al. Rapid response in the COVID-19 pandemic: a Delphi study from the European Pediatric Dialysis Working Group. Pediatr Nephrol (2020).

Francisco R, Brasil S, Pascoal C, Edmondson AC, Jaeken J, Videira PA, de Freitas C, Ferreira VdR, Marques-da-Silva D. A Community-Led Approach as a Guide to Overcome Challenges for Therapy Research in Congenital Disorders of Glycosylation. International Journal of Environmental Research and Public Health. 2022; 19(11):6829.

Dayan I, Roth HR, Zhong A, Harouni A, Gentili A, Abidin AZ, Liu A, Costa AB, Wood BJ, Tsai CS, Wang CH, Hsu CN, Lee CK, Ruan P, Xu D, Wu D, Huang E, Kitamura FC, Lacey G, de Antônio Corradi GC, Nino G, Shin HH, Obinata H, Ren H, Crane JC, Tetreault J, Guan J, Garrett JW, Kaggie JD, Park JG, Dreyer K, Juluru K, Kersten K, Rockenbach MABC, Linguraru MG, Haider MA, AbdelMaseeh M, Rieke N, Damasceno PF, E Silva PMC, Wang P, Xu S, Kawano S, Sriswasdi S, Park SY, Grist TM, Buch V, Jantarabenjakul W, Wang W, Tak WY, Li X, Lin X, Kwon YJ, Quraini A, Feng A, Priest AN, Turkbey B, Glicksberg B, Bizzo B, Kim BS, et al. Federated learning for predicting clinical outcomes in patients with COVID-19. Nat Med. 2021 Oct;27(10):1735-1743. doi: 10.1038/s41591-021-01506-3.

Fakhrudin N, Ladurner A, Atanasov AG, Heiss EH, Baumgartner L, Markt P, Schuster D, Ellmerer EP, Wolber G, Rollinger JM, Stuppner H, Dirsch VM. Computer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gamma. Mol Pharmacol. 2010 Apr;77(4):559-66. doi: 10.1124/mol.109.062141

Medic G, Kosaner Kließ M, Atallah L, Weichert J, Panda S, Postma M, El-Kerdi
A. Evidence-based Clinical Decision Support Systems for the prediction and
detection of three disease states in critical care: A systematic literature
. F1000Res. 2019 Oct 8 ;8:1728. doi: 10.12688/f1000research.20498.2.

Oguz R, Diab-Elschahawi M, Berger J, Auer N, Chiari A, Assadian O, Kimberger
O. Airborne bacterial contamination during orthopedic surgery: A randomized
controlled pilot trial
. J Clin Anesth. 2017 May;38:160-164. doi:

Atanasov AG, Zotchev SB, Dirsch VM; International Natural Product Sciences Taskforce, Supuran CT. Natural products in drug discovery: advances and opportunities. Nat Rev Drug Discov. 2021 Mar;20(3):200-216. doi: 10.1038/s41573-020-00114-z

Patton DE, Cadogan CA, Ryan C, Francis JJ, Gormley GJ, Passmore P, Kerse N, Hughes CM. Improving adherence to multiple medications in older people in primary care: Selecting intervention components to address patient-reported barriers and facilitators. Health Expect. 2018 Feb;21(1):138-148. doi: 10.1111/hex.12595.

Bulten W, Pinckaers H, van Boven H, Vink R, de Bel T, van Ginneken B, van der Laak J, Hulsbergen-van de Kaa C, Litjens G. Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study. Lancet Oncol. 2020 Feb;21(2):233-241. doi: 10.1016/S1470-2045(19)30739-9.

Piotrowicz E, Pencina MJ, Opolski G, Zareba W, Banach M, Kowalik I, Orzechowski P, Szalewska D, Pluta S, Glówczynska R, Irzmanski R, Oreziak A, Kalarus Z, Lewicka E, Cacko A, Mierzynska A, Piotrowicz R. Effects of a 9-Week Hybrid Comprehensive Telerehabilitation Program on Long-term Outcomes in Patients With Heart Failure: The Telerehabilitation in Heart Failure Patients (TELEREH-HF) Randomized Clinical Trial. JAMA Cardiol. 2020 Mar 1;5(3):300-308. doi: 10.1001/jamacardio.2019.5006

Wiegele M, Hamp T, Gratz J, Pablik E, Schaden E. Comparison of ROTEM parameters from venous and intraosseous blood. Sci Rep. 2019 Mar 6;9(1):3741. doi: 10.1038/s41598-019-40412-0

Belbin GM, Cullina S, Wenric S, Soper ER, Glicksberg BS, Torre D, Moscati A, Wojcik GL, Shemirani R, Beckmann ND, Cohain A, Sorokin EP, Park DS, Ambite JL, Ellis S, Auton A; CBIPM Genomics Team; Regeneron Genetics Center, Bottinger EP, Cho JH, Loos RJF, Abul-Husn NS, Zaitlen NA, Gignoux CR, Kenny EE. Toward a fine-scale population health monitoring system. Cell. 2021 Apr 15;184(8):2068-2083.e11. doi: 10.1016/j.cell.2021.03.034

Peter Brown, RELISH Consortium, Yaoqi Zhou, Large expert-curated database for benchmarking document similarity detection in biomedical literature search, Database, Volume 2019, 2019, baz085,

Triffterer L, Marhofer P, Sulyok I, Keplinger M, Mair S, Steinberger M, Klug
W, Kimberger O. Forced-Air Warming During Pediatric Surgery: A Randomized
Comparison of a Compressible with a Noncompressible Warming System
. Anesth Analg. 2016 Jan;122(1):219-25. doi: 10.1213/ANE.0000000000001036.

Yeung AW, Leung WK. Review of Radiology: App for Android by the Radiological
Society of North America (RSNA)
. J Digit Imaging. 2017 Feb;30(1):1-3. doi:

Krammel M, Schnaubelt S, Weidenauer D, Winnisch M, Steininger M, Eichelter J, Hamp T, van Tulder R, Sulzgruber P. Gender and age-specific aspects of awareness and knowledge in basic life support. PLoS One. 2018 Jun 12;13(6):e0198918. doi: 10.1371/journal.pone.0198918

Heimerl K, Pichler B, Plunger P. Challenges and strategies in communication with people with dementia and their informal caregivers in community pharmacies – a narrative approach. Scand J Caring Sci. 2019 Nov 21. doi: 10.1111/scs.12789.

Hörner E, Schebesta K, Hüpfl M, Kimberger O, Rössler B. The Impact of
Monitoring on the Initiation of Cardiopulmonary Resuscitation in Children: Friend
or Foe?
Anesth Analg. 2016 Feb;122(2):490-6. doi: 10.1213/ANE.0000000000001049.

Wang D, Uhrin P, Mocan A, Waltenberger B, Breuss JM, Tewari D, Mihaly-Bison J, Huminiecki Ł, Starzyński RR, Tzvetkov NT, Horbańczuk J, Atanasov AG. Vascular smooth muscle cell proliferation as a therapeutic target. Part 1: molecular targets and pathways. Biotechnol Adv. 2018 Nov 1;36(6):1586-1607. doi: 10.1016/j.biotechadv.2018.04.006

Yeung AWK, Azevedo B, Scarfe WC, Bornstein MM. Patient motion image artifacts can be minimized and re-exposure avoided by selective removal of a sequence of basis images from cone beam computed tomography data sets: a case series. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Feb;129(2):e212-e223. doi: 10.1016/j.oooo.2019.07.003.

Akça O, Kurz A, Fleischmann E, Buggy D, Herbst F, Stocchi L, Galandiuk S,
Iscoe S, Fisher J, Apfel CC, Sessler DI; Hypercapnia Trial Investigators.
Hypercapnia and surgical site infection: a randomized trial
. Br J Anaesth. 2013
Nov;111(5):759-67. doi: 10.1093/bja/aet233.

Plunger P, Heimerl K, Tatzer VC, Zepke G, Finsterwald M, Pichler B, Reitinger E. Developing dementia-friendly pharmacies in Austria: a health promotion approach. Health Promot Int. 2019 Jul 10:daz063. doi: 10.1093/heapro/daz063.

Uddin MS, Tewari D, Mamun AA, Kabir MT, Niaz K, Wahed MII, Barreto GE, Ashraf
GM. Circadian and sleep dysfunction in Alzheimer’s disease. Ageing Res Rev. 2020, Apr 16;60:101046. doi: 10.1016/j.arr.2020.101046.

Yeung AW, Leung WK. Review of Docphin: An App for Mobile Access to Medical
. J Digit Imaging. 2017 Apr;30(2):130-132. doi:

Andy Wai Kan Yeung, Nikolay T. Tzvetkov, Vijai K. Gupta, Subash C. Gupta, Gorka Orive, Günther K. Bonn, Bernd Fiebich, Anupam Bishayee, Thomas Efferth, Jianbo Xiao, Ana Sanches Silva, Gian Luigi Russo, Maria Daglia, Maurizio Battino, Ilkay Erdogan Orhan, Ferdinando Nicoletti, Michael Heinrich, Bharat Bhushan Aggarwal, Marc Diederich, Maciej Banach, Wolfram Weckwerth, Rudolf Bauer, George Perry, Edward A. Bayer, Lukas A. Huber, Jean-Luc Wolfender, Robert Verpoorte, Francisco A. Macias, Michael Wink, Marc Stadler, Simon Gibbons, Alejandro Cifuentes, Elena Ibanez, Gérard Lizard, Rolf Müller, Michael Ristow, Atanas G. Atanasov, Current research in biotechnology: Exploring the biotech forefront, Current Research in Biotechnology, Volume 1, 2019, Pages 34-40,

Kletečka-Pulker M, Völkl-Kernstock S, Fassl A, Klager E, Willschke H, Klomfar S, Wochele-Thoma T, Schaden E, Atanasov AG. Telehealth in Times of COVID-19: Spotlight on Austria. Healthcare (Basel). 2021 Mar 4;9(3):280. doi: 10.3390/healthcare9030280

Stricker KH, Kimberger O, Schmidlin K, Zwahlen M, Mohr U, Rothen HU. Family
satisfaction in the intensive care unit: what makes the difference?
Care Med
. 2009 Dec;35(12):2051-9. doi: 10.1007/s00134-009-1611-4.

Gottesman O, Johansson F, Komorowski M, Faisal A, Sontag D, Doshi-Velez F, Celi LA. Guidelines for reinforcement learning in healthcare. Nat Med. 2019 Jan;25(1):16-18. doi: 10.1038/s41591-018-0310-5

Eibensteiner F, Ritschl V, Nawaz FA, Fazel SS, Tsagkaris C, Kulnik ST, Crutzen R, Klager E, Völkl-Kernstock S, Schaden E, Kletecka-Pulker M, Willschke H, Atanasov AG. People’s Willingness to Vaccinate Against COVID-19 Despite Their Safety Concerns: Twitter Poll Analysis. J Med Internet Res. 2021 Apr 29;23(4):e28973. doi: 10.2196/28973

Parvanov ED, Petkov PM, Paigen K. Prdm9 controls activation of mammalian recombination hotspots. Science. 2010 Feb 12;327(5967):835. doi: 10.1126/science.1181495

Yeung AW. Review of Radiology Signs App for Android. J Digit Imaging. 2016
Oct;29(5):523-5. doi: 10.1007/s10278-016-9896-7.

Mincholé A, Rodriguez B. Artificial intelligence for the electrocardiogram. Nat Med. 2019 Jan;25(1):22-23. doi: 10.1038/s41591-018-0306-1.

Yeung AWK, Tosevska A, Klager E, Eibensteiner F, Tsagkaris C, Parvanov ED, Nawaz FA, Völkl-Kernstock S, Schaden E, Kletecka-Pulker M, Willschke H, Atanasov AG. Medical and Health-Related Misinformation on Social Media: Bibliometric Study of the Scientific Literature. J Med Internet Res. 2022 Jan 25;24(1):e28152. doi: 10.2196/28152

van der Laak J, Litjens G, Ciompi F. Deep learning in histopathology: the path to the clinic. Nat Med. 2021 May;27(5):775-784. doi: 10.1038/s41591-021-01343-4. .